ENME

ENME 481 - Lab-on-a-Chip Microsystems

3 Credits

Instructor 

Textbook 

None. Course handouts.

Description 

Fundamentals and application of lab-on-a-chip and microfluidic technologies. A broad view of the field of microfluidics, knowledge of relevant fabrication methods and analysis techniques, and an understanding of the coupled multi-domain phenomena that dominate the physics in these systems. 

Goals 

Students will develop a broad view of the field of microfluidics, knowledge of relevant fabrication methods and analysis techniques, and an understanding of the couples multi-domain and size-dependent phenomena that dominate the physics in these systems. Microfluidic fabrication techniques, relevant transport processes, flow control methods, molecular separations, and techniques for analyte detection in microfluidic systems will be emphasized. The course culminates with an individual project in which students demonstrate mastery of basic concepts in microfluidic modeling design, and fabrication toward a specific application selected in consultation with the instructor. 

Topics 

  • Scaling in microfluidics
  • Microfabrication and nanofabrication
  • Statics and kinematics of Newtonian fluids
  • Poiseuille and Couette flows; hyrdaulic circuits
  • Diffusion
  • Coupled convection and diffusion
  • Electrokinetic transport, electrophoresis
  • Dielectrophoresis, acoustophoresis
  • Digital microfluidics
  • Surface tension in microfluids
  • Droplet microfluidics
  • Chemical and biochemical separations
  • Flow control (pumps and valves)
  • Analyte detection

Class/Laboratory Schedule 

  • Two 75 minute lectures per week

Last Updated By 
Jessica Stein, August 2017